The variations in urinary calculi are based on different diameters, which range in the form of sand grain to a urinary collecting system so that it can pass through the urinary tract regardless of any symptoms. To determine the composition of urinary calculi for patients in Northern Jordan by using Fourier Transform Infrared Spectroscopy method, samples of urinary calculi were retrieved from patients at King Abdullah University Hospital and Princess Basma Teaching Hospital. Urinary calculi were surgically removed from patients either arthroscopically (n = 35), or by percutaneous nephrolithotomy (PCNL) (n = 15) over a period of 16 months (2013-2014) and were brought to the laboratory in sterile containers. They were analyzed by Fourier Transform Infrared Spectroscopy method. A total of 39 male patients (78%) aging 23-85 years and 11 female patients (22%) aging 33-69 years were included in the study. The calculi comprised of 40% calcium oxalate and uric acid, 24% calcium oxalate, 18% pure uric acid, 12% magnesium ammonium phosphate, and 6% calcium oxalate and calcium phosphate. Mixed urinary calculi of calcium oxalate and uric acid were predominantly found among the patients with the following characteristic IR bands [1637cm-1 C=C Stretching, 1021 cm-1 N-H stretching, 780 cm-1 aromatic C-N stretching].
Coe FL, Evan A, Worcester E. Urinary calculi disease. J Clin Invest. 2005; 115: 2598-608.
De Yoreo JJ, Qiu SR, Hoyer JR. Molecular modulation of calcium oxalate crystallization. Am J Physiol Renal Physiol. 2006; 291: F1123-32.
Kok DJ. Clinical implications of physicochemistry of calculi formation. Endocrinol Metab Clin North Am. 2002; 31: 855-67.
Brown CM, Purich DL (1992) Physical-chemical processes in kidney stone formation. In: Disorders of Bone and Mineral Metabolism. Coe FL, Favus MJ (eds.). Raven Press, New York. pp. 613-624.Parks JH, Coward M, Coe FL. Correspondence between calculi composition and urine supersaturation in nephrolithiasis. Urinary Int. 1997; 51: 894-900.
Burtis CA, Ashwood ER, Bruns DE. Tietz Fundamentals of Clinical Chemistry. (6th ed.). St Louis: Elsevier, 2008: 651.
Yencilek F, Erturhan S, Canguven O, Koyuncu H, Erol B, Kemal S. Does tamsulosin change the management of proximally located ureteral calculi? Urol Res. 2010; 38: 195-9.
Preminger GM. American Urological Association Education and Research Inc. European Association of Urology, Eur Urol. 2007; 52: 1610-31
Ramos-Fernandez M, Serrano LA. Evaluation and management of renal colic in the emergency department. Bol Asoc Med P R. 2009; 101: 29-32.
Esquena S, Millán Rodríguez F, Sánchez-Martín FM, Rousaud Barón F, Marchant F, Villavicencio Mavrich H. Renal colic: Literature review and scientific evidence. Actas Urologicas Espanolas, 2006; 30(3): 268-80.
Shokeir AA, Mahran MR, Abdulmaaboud M. Renal colic in pregnant women: role of renal resistive index, Urology, 2000; 55: 344-7.
Sas DJ. An update on the changing epidemiology and metabolic risk factors in pediatric urinary calculi disease. Clin J Am Soc Nephrol, 2011; 6: 2062.
Asplin JR, Favus MJ, Coe FL. Nephrolitiasis. in Brenner and Rector’s the urinary. (5th ed.). Philadelphia: Saunders. 1996: 1893-935.
Bulo A, Refatllari E, Koci K, Zaganjori R, Isaraj A. Infrared spectroscopy in urinary and biliary calculi disease. Jugoslovenska medicinska biohemija. 2004; 23: 285-8.
Stamatelou KK, Francis ME, Jones CA, Nyberg LM, Curhan GC. Time trends in reported prevalence of urinary calculi in the United States: 1976–1994. Urinary Int., 2003; 63:1817–23.
Zawawi HTH. Wet versus dry chemical analysis of renal stones. Irish Journal of Medical Science, 1999: 114–118.
Singh I. Renal geology (quantitative renal stone analysis) by 'Fourier transform infrared spectroscopy'. Int Urol Nephrol., 2008; 40; 595-602.
Richet G. The chemistry of urinary calculi around 1800: a first in clinical chemistry. Urinary Int., 1995; 48: 876-86.
Pak CY, Peterson R, Sakhaee K, Fuller C, Preminger G, Reisch J. Correction of hypocitraturia and prevention of calculi formation by combined thiazide and potassium citrate therapy in thiazide-unresponsive hypercalciuric nephrolithiasis. Am J Med., 1985; 79: 284–8.
Jungers P, Daudon M, Duke A. Epidemiology of urolithiasis. Urinary lithiasis. Paris: Flammarion medicine-sciences. 1989; 1-34.
Khan AH, Imran S, Talati J, and Jafril L. Fourier Transform Infrared Spectroscopy for Analysis of Kidney Stones. Investigative and Clinical Urology, 2018; 59(1): 32-37.
Ljunghall S, Lithell H, Skarfors E. Prevalence of renal calculi in 60-year-old men. A 10-year follow-up study of a health survey. Br J Urol., 1987; 60: 10-3.
Silverstein RM, Webster FX, Kiemle DJ. Spectrometric identification of organic compounds. (7th Ed.), New York, John Wiley and Sons, Inc., 2005: 72-126.
Heilberg IP, Schor N. Renal calculi disease: causes, evaluation and medical treatment. Arq Bras Endocrinol Metab., 2006; 50: 823-31.
Henderson MJ. Calculi analysis is not useful in the routine investigation of renal calculi disease. Annals of Clinical Biochemistry. 1995; 32: 109–111.
Singh I. Renal geology (quantitative renal calculi analysis) by Fourier transform infrared spectroscopy. Int Urol Nephrol. 2008; 40: 595-602.
Ye Z, Zeng G, Huan Y, Li J, Tang K, Wang G, Wang S, et al. The Status and Characteristics of Urinary Stone Composition in China. Bju International, 8 April 2019. DOI: 10.1111/bju.14765.
Sekkoum K, Cheriti A, Taleb S, and Belboukhari N. FTIR spectroscopic study of human urinary stones from El Bayadh district (Algeria). Arabian Journal of Chemistry, 2016; 9, 330–334.
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