Evaluation of Anthelmintic Activity of Methanolic Extract of Croton Bonplandianum Baill

The aim of the present study was to evaluate the phytochemical constituent and anthelmintic activity of methanolic extract of whole parts of Croton bonplandianum Baill. The various concentration i.e. 100%, 50%, and 25% of methanolic extract of the whole part of Croton bonplandianum Baill were tested for bioassay which determined the time of paralysis (P) the time of death (D) of Pheretima posthuma. Albendazole was used as a standard drug and the normal saline solution was used as controlled. The three different concentrations of plant extract i.e. 25 mg/ml, 50 mg/ml, and 100 mg/ml showed paralysis time 21±1 min, 17±1 min, and 13±2min respectively, and showed death time 51±2 min, 47±1 min, and 41±1 min respectively. Albendazole as a standard drug, in three different concentrations i.e. 25 mg/ml, 50 mg/ml, and 100 mg/ml showed paralysis times 16±1 min, 10±2 min, and 7±2 min respectively, and showed death times 31±2 min, 22±2 min, and 18±3 min respectively. From the result, it is concluded that the methanolic extract of Croton bonplandianum Baill has significant Anthelmintic activity.