European Journal of Advanced Chemistry Research

Synthesis and Characterization of 5-(p-nitro benzyl)-2,3-dihydro-1,3,4-oxadiazole-2-one: A Possible Prosthetic Group for Indirect Radiolabeling of Carbonyl-Containing Compounds

Barakat Moh’d Amin Mah’d Shabsoug — Wed, 14 May 2025 00:00:00 +0200

5-(p-nitro benzyl)-2,3-dihydro-1,3,4-oxadiazole-2-one was prepared in a two-step process. A new β-Carboethoxy hydrazine was prepared first, and then, a new 1,3,4-oxadiazole-2-one, was prepared, both new compounds were identified by MP, IR, 1H NMR, and elemental analysis. The new 1,3,4-oxadiazole-2-one is a possible prosthetic group when iodinated, it could be approved as a method for indirect radiolabeling of carbonyl-containing compounds.

Barakat Moh’d Amin Mah’d Shabsoug

Investigation and Characterization of Alkaloidic Compounds from Apium graveolens and Estimation of their Antibacterial Activity

Jumana Najem Ahmed, Tahreer Fadil Abbas, Abbas Dawwas Matter Al-Maliki — Sat, 21 Sep 2024 00:00:00 +0200

Apium graveolens is considered as one of traditional food plant spreading in various contries in the world and it has the excellent medical efficacy against diverse diseases. Three alkaloidic compounds were isolated, separated. and charaeterized by using gaschromatography-mas spectroscopy analysis. Also the mixture if there active chemical compounds was tested qualitatively using Dragendroff reagent Various concentrations are represented by 10, 25, 35, 50 and 65 mg ⁄ml were prepared from the alkaloidic mixture They recorded different inhibition diameters values equal to 3 , 13 , 21 , 23 and 25 mm against growth of Staphylococcus bacteria. while the same concentrations showed inhibition values are represented by 11 , 21 , 23 , 25and 27 mm towards Bacillus subtillus bacteria. It was noticed that five alkaloidic compounds mixture was more effective against Bacillus subtillus than Staphylococcus aureus bacteria. As a result, the active alkaloids can be used as potent natural therapy for diverse diseases caused by these pathogenic bacteria .

Jumana Najem Ahmed, Tahreer Fadil Abbas, Abbas Dawwas Matter Al-Maliki

Phytochemical Identification of Alkaloidic Compounds from Cinnamomum cassia Cortex and Estimation of their Antifungal Efficacy

Raneen Salim Swadi, Khansaa Saqr Saud, Abbas Dawwas Matter Al-Maliki — Sat, 31 Aug 2024 00:00:00 +0200

Cinnamomum caresia is defined as a medical and traditional plant grows in diverse countries in the world. It has therapeutic effects for treating various diseases resulting from infection by different microorganisms. In the current study, six alkaloids compounds were isolated and characterized from cinamom cortexes by using the GC-MS technique. The synergistic interaction was applied for the alkaloidic mixture against growth of two isolates of pathogenic fungi represented by Urocystis agropyri and Candida albicans by using the concentrations (25, 50, 75, 100, and 125 mg/ml) which recorded diverse diameters of inhibition equal to 58, 66, 72, 74, and 78 mm and 68, 52, 70, 72, and 74 mm, respectively. As a result, these alkaloidic compounds are recommended for use as natural therapy for diseases caused by the current pathogenic fungi.

Raneen Salim Swadi, Khansaa Saqr Saud, Abbas Dawwas Matter Al-Maliki

Characterization of Fipronil in Micellar Medium with Brij 35

Tue, 14 May 2024 00:00:00 +0200

Fipronil is a phenyl pyrazole used as an insecticide to combat termites, moths, and locusts. Its low solubility in water represents a problem with its commercial formulations. In this work, an aqueous micellar medium was formed with Brij 35, calculating the critical micellar concentration at 0.01% (w/v) by UV-visible spectrophotometry and conductimetry. In this medium, the apparent pka was estimated at 12.6 from spectrophotometric data by the graphical method and Partial Least Squares Regression. Finally, its degradation kinetics in this medium at pH 12 was studied, finding that it conforms to a first-order model, with a half-life of 3.3 h, higher than the 2.4 h reported by other authors for an aqueous medium. In conclusion, the micellar medium favored the solubility of the compound in aqueous medium, allowing the estimation of its pka and retarding its chemical degradation.

Eduardo Esteban Reyes-Sánchez, Miguel Velázquez-Manzanares, María del Rocío Gutiérrez-Ortiz, Judith Amador-Hernández

Adsorption Behavior Investigation of Congored onto Nano-Magnetic Cupper-Nickel Ferrites Surface

Atyaf Mirdan Kadhem, Tariq Zbare Jassim — Mon, 13 May 2024 00:00:00 +0200

Ferrite nanoparticles (NPS) of the structure CuNiFe2O4 were synthesized, and the auto combustion process was done using sol-gel. Several methods and nanomaterials have been identified using approaches such as Fourier- Transform Infrared Spectroscopy (FT-IR), X-Ray diffraction (XRD), and Filled Emission Scanning Electron Microscopy (FE-SEM). Measurements were made on the impact of temperature, pH, and contraction on the uptake behavior of CR dye. The ideal duration of interaction to achieve balance is 240 min, and the pH levels fall between 3 and 11. When compared to the Freundlich model, the desorption data demonstrated a good connection with the Lengmuir model. The thermodynamic parameters showed that ∆H was an exothermic reaction, ∆G was a spontaneous process, and ∆S had a negative value, indicating that the process was less disorderly and unpredictable.

Atyaf Mirdan Kadhem, Tariq Zbare Jassim